Mus musculus Protein: Sprr2i
Summary
InnateDB Protein IDBP-168540.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sprr2i
Protein Name small proline-rich protein 2I
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000043513
InnateDB Gene IDBG-168538 (Sprr2i)
Protein Structure
UniProt Annotation
Function Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Not expressed in uterus. {ECO:0000269PubMed:15232223}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008544 epidermis development
GO:0030216 keratinocyte differentiation
GO:0031424 keratinization
Cellular Component
GO:0001533 cornified envelope
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1330309
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O70560
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 20763
UniGene Mm.196439
RefSeq NP_035605
MGI ID
MGI Symbol Sprr2i
OMIM
CCDS CCDS38511
HPRD
IMGT
EMBL AJ005567 AY158993
GenPept AAN86830 CAA06596