InnateDB Protein
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IDBP-168620.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Sprr1b
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Protein Name
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small proline-rich protein 1B
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000058617
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InnateDB Gene
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IDBG-168618 (Sprr1b)
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Protein Structure
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Function |
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
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Subcellular Localization |
Cytoplasm.
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Disease Associations |
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Tissue Specificity |
Expressed in fetal periderm, hair follicles and in the thickened epidermis of the lip and footpad. Also present in the epithelia of various tissues such as the penis, vagina, forestomach, tongue and esophagus.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0005200
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structural constituent of cytoskeleton
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:106659
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InterPro |
IPR003302
Cornifin (SPRR1)
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PFAM |
PF02389
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q62267
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
20754
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UniGene |
Mm.140151
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RefSeq |
NP_033291
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MGI ID |
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MGI Symbol |
Sprr1b
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OMIM |
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CCDS |
CCDS17557
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HPRD |
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IMGT |
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EMBL |
AK003398
AK009752
BC119288
BC119290
U66820
X91825
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GenPept |
AAD10127
AAI19289
AAI19291
BAB22763
BAB26478
CAA62934
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