Version 5.4
Mus musculus Protein: Zxdc
Summary
InnateDB Protein IDBP-168660.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zxdc
Protein Name ZXD family zinc finger C
Synonyms A930012H20; B930086F11Rik; BC003332;
Species Mus musculus
Ensembl Protein ENSMUSP00000036329
InnateDB Gene IDBG-168658 (Zxdc)
Protein Structure
UniProt Annotation
Function Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0030275 LRR domain binding
GO:0046872 metal ion binding
GO:0070742 C2H2 zinc finger domain binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1933108
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C8V1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 80292
UniGene Mm.473652
RefSeq NP_084536
MGI ID
MGI Symbol Zxdc
OMIM
CCDS CCDS51848
HPRD
IMGT
EMBL AK044429 AK044529 AK047538 AK080307 AK081005 AK141613 AK169517 BC003332
GenPept AAH03332 BAC31914 BAC31967 BAC33082 BAC37873 BAC38113 BAE24766 BAE41206

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca