Version 5.4
Mus musculus Protein: Sprr4
Summary
InnateDB Protein IDBP-168682.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sprr4
Protein Name small proline-rich protein 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000051559
InnateDB Gene IDBG-168680 (Sprr4)
Protein Structure
UniProt Annotation
Function Cross-linked envelope protein of keratinocytes. Involved in UV-induced cornification (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Note=Translocates to the cell periphery of keratinocytes and is integrated into both rigid and fragile cornified envelopes. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0031424 keratinization
Cellular Component
GO:0005575 cellular_component
GO:0005938 cell cortex
Protein Structure and Domains
PDB ID MGI:2654508
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CGN8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 229562
UniGene Mm.246590
RefSeq NP_775093
MGI ID
MGI Symbol Sprr4
OMIM
CCDS CCDS38513
HPRD
IMGT
EMBL AY158996 BC107019
GenPept AAI07020 AAN86833

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca