Version 5.4
Mus musculus Protein: Dnmbp
Summary
InnateDB Protein IDBP-168813.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnmbp
Protein Name dynamin binding protein
Synonyms 2410003L07Rik; 2410003M15Rik; TUBA;
Species Mus musculus
Ensembl Protein ENSMUSP00000026209
InnateDB Gene IDBG-168811 (Dnmbp)
Protein Structure
UniProt Annotation
Function Scaffold protein that links dynamin with actin- regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi. {ECO:0000269PubMed:14506234}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:14506234}. Golgi apparatus, Golgi stack {ECO:0000269PubMed:14506234}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:14506234}. Cell junction, synapse {ECO:0000269PubMed:14506234}. Note=Localized to synapses and Golgi stacks.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032319 regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0005795 Golgi stack
GO:0005856 cytoskeleton
GO:0030054 cell junction
GO:0045202 synapse
Protein Structure and Domains
PDB ID MGI:1917352
InterPro IPR000219 Dbl homology (DH) domain
IPR001452 SH3 domain
IPR004148 BAR domain
IPR011511 Variant SH3 domain
IPR013315 Spectrin alpha chain, SH3 domain
PFAM PF00621
PF00018
PF14604
PF03114
PF07653
PRINTS PR00452
PR01887
PIRSF
SMART SM00325
SM00326
SM00721
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6TXD4
PhosphoSite PhosphoSite-Q6TXD4
TrEMBL Q9CWU8
UniProt Splice Variant
Entrez Gene 71972
UniGene Mm.159024
RefSeq NP_082305
MGI ID
MGI Symbol Dnmbp
OMIM
CCDS CCDS29839
HPRD
IMGT
EMBL AK010367 AK010372 AK129261 AY383729 BC025944
GenPept AAH25944 AAQ81299 BAB26890 BAC25293 BAC98071

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca