Version 5.4
Mus musculus Protein: Pof1b
Summary
InnateDB Protein IDBP-168843.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pof1b
Protein Name premature ovarian failure 1B
Synonyms 2310066B14Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000047655
InnateDB Gene IDBG-168841 (Pof1b)
Protein Structure
UniProt Annotation
Function Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development (By similarity). {ECO:0000250}.
Subcellular Localization Cell junction, tight junction {ECO:0000250}.
Disease Associations
Tissue Specificity Expression absent in adult ovary. {ECO:0000269PubMed:15459172}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID MGI:1916943
InterPro IPR009053 Prefoldin
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K4L4
PhosphoSite PhosphoSite-Q8K4L4
TrEMBL
UniProt Splice Variant
Entrez Gene 69693
UniGene Mm.34964
RefSeq NP_853557
MGI ID
MGI Symbol Pof1b
OMIM
CCDS CCDS30362
HPRD
IMGT
EMBL AF309775 AF408412 AK086511 AL831771 CH466564
GenPept AAM00425 AAM93271 BAC39681 CAM21383 EDL14003

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca