Version 5.4
Mus musculus Protein: Gabrg1
Summary
InnateDB Protein IDBP-168855.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gabrg1
Protein Name gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
Synonyms GabaA; GabaA/BZ;
Species Mus musculus
Ensembl Protein ENSMUSP00000031119
InnateDB Gene IDBG-168853 (Gabrg1)
Protein Structure
UniProt Annotation
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular Localization Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004890 GABA-A receptor activity
GO:0005230 extracellular ligand-gated ion channel activity
GO:0005254 chloride channel activity
GO:0050811 GABA receptor binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0007268 synaptic transmission
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0034707 chloride channel complex
GO:0043235 receptor complex
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID MGI:103156
InterPro IPR001390 Gamma-aminobutyric-acid A receptor, alpha subunit
IPR005437 Gamma-aminobutyric-acid A receptor, gamma subunit
IPR005438 Gamma-aminobutyric-acid A receptor, gamma 1 subunit
IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding
PFAM PF02932
PF02931
PRINTS PR01079
PR01620
PR01621
PR00253
PR00252
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9R0Y8
PhosphoSite PhosphoSite-Q9R0Y8
TrEMBL O88965
UniProt Splice Variant
Entrez Gene 14405
UniGene Mm.466102
RefSeq NP_034382
MGI ID
MGI Symbol Gabrg1
OMIM
CCDS CCDS19326
HPRD
IMGT
EMBL AC068252 AC092716 AF090375 AK034332 AK038468 AK047752 AK049956 BC099939 CH466524 X55272
GenPept AAC35562 AAH99939 BAC28677 BAC33146 BAC34006 BAE43302 CAA38992 EDL37806

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca