Mus musculus Protein: Arrdc3
Summary
InnateDB Protein IDBP-169504.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arrdc3
Protein Name arrestin domain containing 3
Synonyms AI450344; mKIAA1376;
Species Mus musculus
Ensembl Protein ENSMUSP00000096957
InnateDB Gene IDBG-169502 (Arrdc3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm. Note=Associated with plasma membrane, as well as with endodomes and lysosomes during endocytosis. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0031699 beta-3 adrenergic receptor binding
Biological Process
GO:0001659 temperature homeostasis
GO:0031651 negative regulation of heat generation
GO:0043588 skin development
GO:0044252 negative regulation of multicellular organismal metabolic process
GO:0051443 positive regulation of ubiquitin-protein transferase activity
GO:0060613 fat pad development
GO:0071879 positive regulation of adrenergic receptor signaling pathway
GO:0090327 negative regulation of locomotion involved in locomotory behavior
Cellular Component
GO:0005768 endosome
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:2145242
InterPro IPR011021 Arrestin-like, N-terminal
IPR011022 Arrestin C-terminal-like domain
IPR014756 Immunoglobulin E-set
PFAM PF00339
PF02752
PRINTS
PIRSF
SMART SM01017
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TPQ9
PhosphoSite PhosphoSite-Q7TPQ9
TrEMBL Q0GJK3
UniProt Splice Variant
Entrez Gene 105171
UniGene Mm.428101
RefSeq NP_001036056
MGI ID
MGI Symbol Arrdc3
OMIM
CCDS CCDS36736
HPRD
IMGT
EMBL AK122499 BC031125 BC054844 BC098474 CT009711 DQ861994
GenPept AAH31125 AAH54844 AAH98474 ABI20767 BAC65781