Version 5.4
Mus musculus Protein: S100a11
Summary
InnateDB Protein IDBP-169521.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100a11
Protein Name S100 calcium binding protein A11 (calgizzarin)
Synonyms cal; Emap1; EMAPI; S100a14; S100c;
Species Mus musculus
Ensembl Protein ENSMUSP00000029515
InnateDB Gene IDBG-169519 (S100a11)
Protein Structure
UniProt Annotation
Function Facilitates the differentiation and the cornification of keratinocytes. {ECO:0000250}.
Subcellular Localization Cytoplasm. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0044548 S100 protein binding
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0001726 ruffle
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1338798
InterPro IPR002048 EF-hand domain
IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
PFAM PF00036
PF13202
PF13405
PF01023
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P50543
PhosphoSite PhosphoSite-P50543
TrEMBL
UniProt Splice Variant
Entrez Gene 277089
UniGene Mm.426050
RefSeq NP_058020
MGI ID
MGI Symbol S100a11
OMIM
CCDS CCDS38525
HPRD
IMGT
EMBL AK002490 AK003889 AK164352 BC021916 BC086903 U41341
GenPept AAA85181 AAH21916 AAH86903 BAB22139 BAB23059 BAE37754

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca