InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Zfp354a

Summary

InnateDB Protein

IDBP-169551.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zfp354a

Protein Name

zinc finger protein 354A

Synonyms

AW488485; kid1; Tcf17; Znf354a;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099827

InnateDB Gene

IDBG-169549 (Zfp354a)

Protein Structure

UniProt Annotation

Function

It may play a role in renal development and may also be involved in the repair of the kidney after ischemia-reperfusion or folic acid administration.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Highly expressed in eye and kidney. Detected at high levels in adult brain and kidney, and at lower levels in adult liver, lung, skeletal muscle, heart, salivary gland, testis and tongue. Detected in embryonic brain, heart, lung,kidney and gut. {ECO:0000269PubMed:10564808}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001666	response to hypoxia
GO:0001822	kidney development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007576	nucleolar fragmentation
GO:0051593	response to folic acid