Version 5.4
Mus musculus Protein: Tmem149
Summary
InnateDB Protein IDBP-170157.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem149
Protein Name transmembrane protein 149
Synonyms F630003I17Rik; Tmem149;
Species Mus musculus
Ensembl Protein ENSMUSP00000042312
InnateDB Gene IDBG-170153 (Tmem149)
Protein Structure
UniProt Annotation
Function Probable cell membrane receptor for the IGF-like family protein IGFL. {ECO:0000269PubMed:21454693}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:21454693}; Single-pass type I membrane protein {ECO:0000269PubMed:21454693}.
Disease Associations
Tissue Specificity Ubiquitously expressed with higher expression in lymph node. Highly expressed in T-cells and monocytes. {ECO:0000269PubMed:21454693}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3655979
InterPro IPR011029 Death-like domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3U4N7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 101883
UniGene Mm.333757
RefSeq NP_663555
MGI ID
MGI Symbol Igflr1
OMIM
CCDS CCDS39886
HPRD
IMGT
EMBL AK154129 BC019733
GenPept AAH19733 BAE32394

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca