Version 5.4
Mus musculus Protein: Slc10a4
Summary
InnateDB Protein IDBP-170427.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc10a4
Protein Name solute carrier family 10 (sodium/bile acid cotransporter family), member 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000031127
InnateDB Gene IDBG-170425 (Slc10a4)
Protein Structure
UniProt Annotation
Function Transporter for bile acids. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Highest expression in the brain and significantly above background levels in the eye, prostate, and whole embryo tissue preparations. {ECO:0000269PubMed:18355966}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008508 bile acid:sodium symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0015721 bile acid and bile salt transport
GO:0030534 adult behavior
GO:0042493 response to drug
GO:0055085 transmembrane transport
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3606480
InterPro IPR002657 Bile acid:sodium symporter
PFAM PF01758
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UEZ8
PhosphoSite PhosphoSite-
TrEMBL A2RTJ6
UniProt Splice Variant
Entrez Gene 231290
UniGene Mm.490630
RefSeq NP_775579
MGI ID
MGI Symbol Slc10a4
OMIM
CCDS CCDS19336
HPRD
IMGT
EMBL AK087479 AK149202 BC132529 BC138048 CH466524
GenPept AAI32530 AAI38049 BAC39890 BAE28763 EDL37841

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca