Version 5.4
Mus musculus Protein: Rbm42
Summary
InnateDB Protein IDBP-170712.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rbm42
Protein Name RNA binding motif protein 42
Synonyms 1700003D06Rik; 3100004P22Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000040005
InnateDB Gene IDBG-170710 (Rbm42)
Protein Structure
UniProt Annotation
Function Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000269PubMed:19170760}. Cytoplasm {ECO:0000269PubMed:19170760}. Note=Upon stress response, localizes with HNRNPK in cytoplasmic aggregates of stalled translational preinitiation complexes called stress granules.
Disease Associations
Tissue Specificity Expressed in cell lines (at protein level). Expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis. {ECO:0000269PubMed:19170760}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1915285
InterPro IPR000504 RNA recognition motif domain
PFAM PF00076
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91V81
PhosphoSite PhosphoSite-Q91V81
TrEMBL
UniProt Splice Variant
Entrez Gene 68035
UniGene Mm.401747
RefSeq NP_598454
MGI ID
MGI Symbol Rbm42
OMIM
CCDS CCDS52179
HPRD
IMGT
EMBL AK151000 BC009148 BC011286 BC027372 BC057928
GenPept AAH09148 AAH11286 AAH27372 AAH57928 BAE30024

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca