Version 5.4
Mus musculus Protein: Resp18
Summary
InnateDB Protein IDBP-170720.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Resp18
Protein Name regulated endocrine-specific protein 18
Synonyms AI851012;
Species Mus musculus
Ensembl Protein ENSMUSP00000043783
InnateDB Gene IDBG-170718 (Resp18)
Protein Structure
UniProt Annotation
Function May play an important regulatory role in corticotrophs.
Subcellular Localization Secreted. Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=Found in the lumen of dense core vesicles (DCV). {ECO:0000250}.
Disease Associations
Tissue Specificity Pituitary, hypothalamus and pancreas. Highest levels are found in somatotrophes, mammotrophes, and gonadotrophes, and lower levels are found in corticotrophs and thyrotropes. {ECO:0000269PubMed:17951542}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0001701 in utero embryonic development
Cellular Component
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0030141 secretory granule
GO:0043204 perikaryon
GO:0048237 rough endoplasmic reticulum lumen
Protein Structure and Domains
PDB ID MGI:1098222
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P47939
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 19711
UniGene Mm.4032
RefSeq NP_033075
MGI ID
MGI Symbol Resp18
OMIM
CCDS CCDS15069
HPRD
IMGT
EMBL AK019440 BC027535 L34214
GenPept AAA67425 AAH27535 BAB31720

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca