InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gypa

Summary

InnateDB Protein

IDBP-170952.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gypa

Protein Name

glycophorin A

Synonyms

AI853584; CD235a; GPA;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000070836

InnateDB Gene

IDBG-170950 (Gypa)

Protein Structure

UniProt Annotation

Function

Glycophorin A is the major intrinsic membrane sialoglycoprotein of the erythrocyte. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane; Single-pass type III membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0007016	cytoskeletal anchoring at plasma membrane
GO:0047484	regulation of response to osmotic stress

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0009897	external side of plasma membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome