Version 5.4
Mus musculus Protein: Gramd4
Summary
InnateDB Protein IDBP-171122.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gramd4
Protein Name GRAM domain containing 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000086321
InnateDB Gene IDBG-171120 (Gramd4)
Protein Structure
UniProt Annotation
Function Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. {ECO:0000250}.
Subcellular Localization Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Note=Colocalizes with COX4I1. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006915 apoptotic process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID MGI:2676308
InterPro IPR004182 GRAM domain
IPR013583 Phosphoribosyltransferase C-terminal
PFAM PF02893
PF08372
PRINTS
PIRSF
SMART SM00568
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CB44
PhosphoSite PhosphoSite-Q8CB44
TrEMBL
UniProt Splice Variant
Entrez Gene 223752
UniGene Mm.405343
RefSeq NP_766199
MGI ID
MGI Symbol Gramd4
OMIM
CCDS CCDS27727
HPRD
IMGT
EMBL AK036832 AK129209 BC021523 BC139228 BC139229
GenPept AAH21523 AAI39229 AAI39230 BAC29597 BAC98019

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca