InnateDB Protein
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IDBP-171217.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Sgcb
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Protein Name
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sarcoglycan, beta (dystrophin-associated glycoprotein)
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Synonyms
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43kDa; AI747103; AI844814; beta-SG;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000079937
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InnateDB Gene
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IDBG-171215 (Sgcb)
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Protein Structure
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Function |
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
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Subcellular Localization |
Cell membrane, sarcolemma {ECO:0000269PubMed:9864373}; Single-pass type II membrane protein {ECO:0000269PubMed:9864373}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:9864373}.
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Disease Associations |
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Tissue Specificity |
Most strongly expressed in skeletal and heart muscle. Also detected in proliferating myoblasts.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
14
[view]
|
Protein-Protein |
14
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1346523
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InterPro |
IPR006875
Sarcoglycan complex subunit protein
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PFAM |
PF04790
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P82349
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PhosphoSite |
PhosphoSite-P82349
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
24051
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UniGene |
Mm.89310
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RefSeq |
NP_036020
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MGI ID |
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MGI Symbol |
Sgcb
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OMIM |
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CCDS |
CCDS19344
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HPRD |
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IMGT |
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EMBL |
AB024921
AF169288
AK014381
AK132306
AK169403
BC052349
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GenPept |
AAF28458
AAH52349
BAA83492
BAB29310
BAE21093
BAE41149
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