Mus musculus Protein: Btnl2 | |||||||
---|---|---|---|---|---|---|---|
Summary | |||||||
InnateDB Protein | IDBP-171372.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Btnl2 | ||||||
Protein Name | butyrophilin-like 2 | ||||||
Synonyms | |||||||
Species | Mus musculus | ||||||
Ensembl Protein | ENSMUSP00000025198 | ||||||
InnateDB Gene | IDBG-171370 (Btnl2) | ||||||
Protein Structure | |||||||
UniProt Annotation | |||||||
Function | Negative regulator of T-cell proliferation. {ECO:0000269PubMed:16751379, ECO:0000269PubMed:17237401}. | ||||||
Subcellular Localization | Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. | ||||||
Disease Associations | |||||||
Tissue Specificity | Highly expressed in intestine and at reduced levels in lung and stomach. Also expressed in thymus, spleen, lymph nodes, T-cells, B-cells, and macrophages. {ECO:0000269PubMed:16751379, ECO:0000269PubMed:17237401}. | ||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
||||||
Gene Ontology | |||||||
Molecular Function |
|
||||||
Biological Process |
|
||||||
Cellular Component |
|
||||||
Protein Structure and Domains | |||||||
PDB ID | MGI:1859549 | ||||||
InterPro |
IPR003596
Immunoglobulin V-set, subgroup IPR003598 Immunoglobulin subtype 2 IPR003599 Immunoglobulin subtype IPR007110 Immunoglobulin-like domain IPR013106 Immunoglobulin V-set domain IPR013162 CD80-like, immunoglobulin C2-set |
||||||
PFAM |
PF07686
PF08205 |
||||||
PRINTS | |||||||
PIRSF | |||||||
SMART |
SM00406
SM00408 SM00409 |
||||||
TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | O70355 | ||||||
PhosphoSite | PhosphoSite- | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 547431 | ||||||
UniGene | Mm.441007 | ||||||
RefSeq | NP_524574 | ||||||
MGI ID | |||||||
MGI Symbol | Btnl2 | ||||||
OMIM | |||||||
CCDS | CCDS37585 | ||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AF050157 AK136521 CR974457 | ||||||
GenPept | AAC05288 BAE23022 CAO77746 | ||||||