Version 5.4
Mus musculus Protein: Acot12
Summary
InnateDB Protein IDBP-171444.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acot12
Protein Name acyl-CoA thioesterase 12
Synonyms 1300004O04Rik; 4930449F15Rik; AV027244; Cach; mCACH-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000022120
InnateDB Gene IDBG-171442 (Acot12)
Protein Structure
UniProt Annotation
Function Hydrolyzes acetyl-CoA to acetate and CoA. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003986 acetyl-CoA hydrolase activity
GO:0005524 ATP binding
GO:0008289 lipid binding
Biological Process
GO:0006084 acetyl-CoA metabolic process
GO:0006090 pyruvate metabolic process
GO:0006631 fatty acid metabolic process
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:1921406
InterPro IPR002913 START domain
IPR006683 Thioesterase superfamily
IPR029069 HotDog domain
PFAM PF01852
PF03061
PRINTS
PIRSF
SMART SM00234
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DBK0
PhosphoSite PhosphoSite-Q9DBK0
TrEMBL A2RSC2
UniProt Splice Variant
Entrez Gene 74156
UniGene Mm.275963
RefSeq NP_083066
MGI ID
MGI Symbol Acot12
OMIM
CCDS CCDS26678
HPRD
IMGT
EMBL AB078618 AK004905 AK034622 BC025852 BC132050 BC137996 CH466567
GenPept AAH25852 AAI32051 AAI37997 BAB23658 BAB84021 BAC28775 EDL00967

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca