Version 5.4
Mus musculus Protein: Tbc1d22a
Summary
InnateDB Protein IDBP-171456.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbc1d22a
Protein Name TBC1 domain family, member 22a
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000065721
InnateDB Gene IDBG-171454 (Tbc1d22a)
Protein Structure
UniProt Annotation
Function May act as a GTPase-activating protein for Rab family protein(s). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0008150 biological_process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1289265
InterPro IPR000195 Rab-GTPase-TBC domain
PFAM PF00566
PRINTS
PIRSF
SMART SM00164
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R5A6
PhosphoSite PhosphoSite-Q8R5A6
TrEMBL
UniProt Splice Variant
Entrez Gene 223754
UniGene Mm.413427
RefSeq NP_663451
MGI ID
MGI Symbol Tbc1d22a
OMIM
CCDS CCDS27729
HPRD
IMGT
EMBL AK039627 AK146872 AK154226 AK154602 AK155459 AK155770 BC023106 BC066009
GenPept AAH23106 AAH66009 BAC30403 BAE27495 BAE32447 BAE32705 BAE33274 BAE33429

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca