InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gpd2

Summary

InnateDB Protein

IDBP-171627.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gpd2

Protein Name

glycerol phosphate dehydrogenase 2, mitochondrial

Synonyms

AA408484; AI448216; AU021455; AW494132; Gdm1; Gpd-m; GPDH; Gpdh-m; TISP38;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000028167

InnateDB Gene

IDBG-171625 (Gpd2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion inner membrane.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0016491	oxidoreductase activity
GO:0052591	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity

Biological Process

GO:0006072	glycerol-3-phosphate metabolic process
GO:0006094	gluconeogenesis
GO:0019563	glycerol catabolic process
GO:0035264	multicellular organism growth
GO:0043010	camera-type eye development
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0009331	glycerol-3-phosphate dehydrogenase complex

Protein Structure and Domains

PDB ID

MGI:99778

InterPro

IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase
IPR002048 EF-hand domain
IPR003953 FAD binding domain
IPR006076 FAD dependent oxidoreductase

PFAM

PF00036
PF13202
PF13405
PF00890
PF01266

PRINTS

PR01001

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt