Version 5.4
Homo sapiens Protein: NIPAL1
Summary
InnateDB Protein IDBP-17166.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NIPAL1
Protein Name NIPA-like domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000295461
InnateDB Gene IDBG-17164 (NIPAL1)
Protein Structure
UniProt Annotation
Function Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0015095 magnesium ion transmembrane transporter activity
Biological Process
GO:0015693 magnesium ion transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000620 Drug/metabolite transporter
IPR008521 Magnesium transporter NIPA
PFAM PF00892
PF05653
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NVV3
PhosphoSite PhosphoSite-Q6NVV3
TrEMBL
UniProt Splice Variant
Entrez Gene 152519
UniGene Hs.736798
RefSeq NP_997213
HUGO HGNC:27194
OMIM
CCDS CCDS3479
HPRD 14096
IMGT
EMBL AK095299 BC067881 CR749484
GenPept AAH67881 BAG53022 CAH18311

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca