InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Creld2

Summary

InnateDB Protein

IDBP-171834.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Creld2

Protein Name

cysteine-rich with EGF-like domains 2

Synonyms

5730592L21Rik; C85758;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000024042

InnateDB Gene

IDBG-171832 (Creld2)

Protein Structure

UniProt Annotation

Function

May regulate transport of alpha4-beta2 neuronal acetylcholine receptor. {ECO:0000250}.

Subcellular Localization

Secreted. Endoplasmic reticulum {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005615	extracellular space
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus

Protein Structure and Domains

PDB ID

MGI:1923987

InterPro

IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR006212 Furin-like repeat
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR021852 Domain of unknown function DUF3456

PFAM

PF00008
PF07645
PF11938

PRINTS

PIRSF

SMART

SM00181
SM00179
SM00261

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CYA0