Version 5.4
Mus musculus Protein: Pprc1
Summary
InnateDB Protein IDBP-171922.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pprc1
Protein Name peroxisome proliferative activated receptor, gamma, coactivator-related 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000079389
InnateDB Gene IDBG-171918 (Pprc1)
Protein Structure
UniProt Annotation
Function Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000269PubMed:11340167}. Note=Colocalizes with NRF1.
Disease Associations
Tissue Specificity Expressed in liver, heart, skeletal muscle, kidney and white and brown adipose tissues. {ECO:0000269PubMed:11340167}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2385096
InterPro IPR000504 RNA recognition motif domain
PFAM PF00076
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NZN1
PhosphoSite PhosphoSite-Q6NZN1
TrEMBL
UniProt Splice Variant
Entrez Gene 226169
UniGene Mm.474645
RefSeq XP_006527073
MGI ID
MGI Symbol Pprc1
OMIM
CCDS
HPRD
IMGT
EMBL AK044522 AK122322 AK147947 BC013720 BC066048
GenPept AAH13720 AAH66048 BAC31964 BAC65604 BAE28245

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca