Mus musculus Protein: Gsx2
Summary
InnateDB Protein IDBP-171925.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gsx2
Protein Name GS homeobox 2
Synonyms Gsh-2; Gsh2;
Species Mus musculus
Ensembl Protein ENSMUSP00000036625
InnateDB Gene IDBG-171923 (Gsx2)
Protein Structure
UniProt Annotation
Function Probable transcription factor that binds to the DNA sequence 5'-CNAATTAG-3'.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity Expressed in the developing brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0002087 regulation of respiratory gaseous exchange by neurological system process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007389 pattern specification process
GO:0007417 central nervous system development
GO:0007420 brain development
GO:0021527 spinal cord association neuron differentiation
GO:0021544 subpallium development
GO:0021575 hindbrain morphogenesis
GO:0021798 forebrain dorsal/ventral pattern formation
GO:0021889 olfactory bulb interneuron differentiation
GO:0021978 telencephalon regionalization
GO:0030334 regulation of cell migration
GO:0045747 positive regulation of Notch signaling pathway
GO:0048663 neuron fate commitment
GO:0048665 neuron fate specification
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0048853 forebrain morphogenesis
GO:0060163 subpallium neuron fate commitment
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:95843
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P31316
PhosphoSite PhosphoSite-
TrEMBL Q3TXX0
UniProt Splice Variant
Entrez Gene 14843
UniGene Mm.218752
RefSeq NP_573555
MGI ID
MGI Symbol Gsx2
OMIM
CCDS CCDS19350
HPRD
IMGT
EMBL AK159070 S79041
GenPept AAB34947 BAE34794