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InnateDB Protein
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IDBP-171943.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ints6
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Protein Name
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integrator complex subunit 6
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Synonyms
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2900075H24Rik; AI480962; Ddx26; DICE1; HDB; Notch2l;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000086788
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InnateDB Gene
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IDBG-171941 (Ints6)
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Protein Structure
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| Function |
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Nucleus {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
3
[view]
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| Protein-Protein |
3
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
42 [view]
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
MGI:1202397
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| InterPro |
IPR002035
von Willebrand factor, type A
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| PFAM |
PF00092
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| PRINTS |
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| PIRSF |
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| SMART |
SM00327
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q6PCM2
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| PhosphoSite |
PhosphoSite-Q6PCM2
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
18130
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| UniGene |
Mm.319684
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| RefSeq |
NP_032741
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| MGI ID |
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| MGI Symbol |
Ints6
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| OMIM |
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| CCDS |
CCDS27191
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| HPRD |
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| IMGT |
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| EMBL |
AK046055
AK172178
BC058637
BC059263
U57368
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| GenPept |
AAB01338
AAH58637
AAH59263
BAC32584
BAE42868
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Version 5.4