InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gpsm3

Summary

InnateDB Protein

IDBP-171984.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gpsm3

Protein Name

G-protein signalling modulator 3 (AGS3-like, C. elegans)

Synonyms

AA960287; AGS4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000045911

InnateDB Gene

IDBG-171982 (Gpsm3)

Protein Structure

UniProt Annotation

Function

Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005092	GDP-dissociation inhibitor activity
GO:0030695	GTPase regulator activity

Biological Process

GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
GO:0050790	regulation of catalytic activity

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:2146785

InterPro

IPR003109 GoLoco motif

PFAM

PF02188

PRINTS

PIRSF

SMART

SM00390

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3U1Z5

PhosphoSite

PhosphoSite-Q3U1Z5

TrEMBL

Q0VGT5

UniProt Splice Variant

Entrez Gene

106512

UniGene

Mm.26584

RefSeq

NP_598877

MGI ID

MGI Symbol

Gpsm3

OMIM

CCDS

CCDS37589

HPRD

IMGT

EMBL

AK146245 AK155617 AK155863 BC021942 BC080804 BC085186 CH466666 CT009767

GenPept

AAH21942 AAH80804 AAH85186 BAE27009 BAE33348 BAE33467 CAM18616 EDL26806 EDL26807