InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ager

Summary

InnateDB Protein

IDBP-172146.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ager

Protein Name

advanced glycosylation end product-specific receptor

Synonyms

RAGE;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000015596

InnateDB Gene

IDBG-172144 (Ager)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042802	identical protein binding
GO:0044548	S100 protein binding

Biological Process

GO:0006954	inflammatory response
GO:0031175	neuron projection development
GO:0045087	innate immune response (InnateDB)
GO:0050930	induction of positive chemotaxis
GO:0051092	positive regulation of NF-kappaB transcription factor activity

Cellular Component

GO:0016020

membrane

Protein Structure and Domains

PDB ID

MGI:893592

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin
IPR013162 CD80-like, immunoglobulin C2-set

PFAM

PF07679
PF00047
PF08205

PRINTS

PIRSF

SMART

SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite