InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pax3

Summary

InnateDB Protein

IDBP-172198.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pax3

Protein Name

paired box gene 3

Synonyms

Pax-3; Sp; splotch;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000004994

InnateDB Gene

IDBG-172194 (Pax3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 45 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	45 [view]
Protein-Protein	37 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	4 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0071837	HMG box domain binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001755	neural crest cell migration
GO:0001843	neural tube closure
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0007507	heart development
GO:0007517	muscle organ development
GO:0008283	cell proliferation
GO:0008284	positive regulation of cell proliferation
GO:0014807	regulation of somitogenesis
GO:0016477	cell migration
GO:0021527	spinal cord association neuron differentiation
GO:0021915	neural tube development
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048066	developmental pigmentation
GO:0048663	neuron fate commitment
GO:0060594	mammary gland specification