InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lgi4

Summary

InnateDB Protein

IDBP-172207.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lgi4

Protein Name

leucine-rich repeat LGI family, member 4

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000041579

InnateDB Gene

IDBG-172205 (Lgi4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Secreted {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0008344	adult locomotory behavior
GO:0014009	glial cell proliferation
GO:0014044	Schwann cell development
GO:0021782	glial cell development
GO:0022011	myelination in peripheral nervous system
GO:0042063	gliogenesis
GO:0042551	neuron maturation
GO:0042552	myelination

Cellular Component

GO:0005615

extracellular space

Protein Structure and Domains

PDB ID

MGI:2180197

InterPro

IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR005492 Leucine-rich glioma-inactivated , EPTP repeat
IPR009039 EAR

PFAM

PF01463
PF00560
PF13504
PF13855
PF03736

PRINTS

PIRSF

SMART

SM00082
SM00369

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K1S1