Version 5.4
Mus musculus Protein: Adpgk
Summary
InnateDB Protein IDBP-172446.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adpgk
Protein Name ADP-dependent glucokinase
Synonyms 2610017G09Rik; Adp-gk; C77577;
Species Mus musculus
Ensembl Protein ENSMUSP00000026266
InnateDB Gene IDBG-172444 (Adpgk)
Protein Structure
UniProt Annotation
Function Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0043843 ADP-specific glucokinase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006096 glycolytic process
GO:0008150 biological_process
GO:0016310 phosphorylation
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1919391
InterPro IPR007666 ADP-specific phosphofructokinase/glucokinase
IPR029056 Ribokinase-like
PFAM PF04587
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VDL4
PhosphoSite PhosphoSite-Q8VDL4
TrEMBL Q3UDS7
UniProt Splice Variant
Entrez Gene 72141
UniGene Mm.396788
RefSeq NP_082397
MGI ID
MGI Symbol Adpgk
OMIM
CCDS CCDS23248
HPRD
IMGT
EMBL AK011434 AK048904 AK149942 BC021526
GenPept AAH21526 BAB27619 BAC33486 BAE29184

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca