InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fkbpl

Summary

InnateDB Protein

IDBP-172574.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fkbpl

Protein Name

FK506 binding protein-like

Synonyms

DIR1; NG7; Ppiase-X; Wisp39;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000037273

InnateDB Gene

IDBG-172572 (Fkbpl)

Protein Structure

UniProt Annotation

Function

May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003755	peptidyl-prolyl cis-trans isomerase activity
GO:0005515	protein binding
GO:0005528	FK506 binding

Biological Process

GO:0000413	protein peptidyl-prolyl isomerization
GO:0018208	peptidyl-proline modification

Cellular Component

GO:0016020

membrane

Protein Structure and Domains

PDB ID

MGI:1932127

InterPro

IPR001440 Tetratricopeptide TPR1
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR019734 Tetratricopeptide repeat

PFAM

PF00515
PF07719
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O35450