Version 5.4
Mus musculus Protein: Nmu
Summary
InnateDB Protein IDBP-173152.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nmu
Protein Name neuromedin U
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000031146
InnateDB Gene IDBG-173150 (Nmu)
Protein Structure
UniProt Annotation
Function Stimulates muscle contractions of specific regions of the gastrointestinal tract. {ECO:0000250}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0042922 neuromedin U receptor binding
Biological Process
GO:0001696 gastric acid secretion
GO:0006940 regulation of smooth muscle contraction
GO:0007218 neuropeptide signaling pathway
GO:0009648 photoperiodism
GO:0019233 sensory perception of pain
GO:0042755 eating behavior
GO:0045987 positive regulation of smooth muscle contraction
GO:0046887 positive regulation of hormone secretion
GO:0050806 positive regulation of synaptic transmission
Cellular Component
GO:0005576 extracellular region
GO:0043195 terminal bouton
Protein Structure and Domains
PDB ID MGI:1860476
InterPro IPR008200 Neuromedin U, C-terminal
PFAM PF02070
PRINTS
PIRSF
SMART SM00084
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QXK8
PhosphoSite PhosphoSite-Q9QXK8
TrEMBL Q9JLQ5
UniProt Splice Variant
Entrez Gene 56183
UniGene Mm.154879
RefSeq NP_062388
MGI ID
MGI Symbol Nmu
OMIM
CCDS CCDS19362
HPRD
IMGT
EMBL AF146793 AF203444 AK077478 BC125545 BC138071 CH466524
GenPept AAF20198 AAF67393 AAI25546 AAI38072 BAC36820 EDL37901

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca