Version 5.4
| Mus musculus Protein: Adamtsl4 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-173248.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Adamtsl4 | ||||||||
| Protein Name | ADAMTS-like 4 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000015994 | ||||||||
| InnateDB Gene | IDBG-173246 (Adamtsl4) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Colocalizes with FMN1 microfibrils in the eye ECM. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Widely expressed in a range of tissues. Especially prevalent in brain, spinal cord, muscle, lung and heart. {ECO:0000269PubMed:12706885}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2389008 | ||||||||
| InterPro |
IPR000884
Thrombospondin, type 1 repeat IPR010294 ADAM-TS Spacer 1 IPR010909 PLAC |
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| PFAM |
PF00090
PF05986 PF08686 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00209
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q80T21 | ||||||||
| PhosphoSite | PhosphoSite-Q80T21 | ||||||||
| TrEMBL | Q91YP4 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 229595 | ||||||||
| UniGene | Mm.490574 | ||||||||
| RefSeq | NP_659148 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Adamtsl4 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS17618 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AY158701 BC016215 BC117925 | ||||||||
| GenPept | AAH16215 AAI17926 AAO17738 | ||||||||