Mus musculus Protein: Glra4 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-173307.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Glra4 | ||||||||||||
Protein Name | glycine receptor, alpha 4 subunit | ||||||||||||
Synonyms | |||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Protein | ENSMUSP00000018739 | ||||||||||||
InnateDB Gene | IDBG-173305 (Glra4) | ||||||||||||
Protein Structure |
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UniProt Annotation | |||||||||||||
Function | The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). May play a role in the maturation of reproductive organs. {ECO:0000269PubMed:10762330}. | ||||||||||||
Subcellular Localization | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | |||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | MGI:95750 | ||||||||||||
InterPro |
IPR006028
Gamma-aminobutyric acid A receptor/Glycine receptor alpha IPR006029 Neurotransmitter-gated ion-channel transmembrane domain IPR006201 Neurotransmitter-gated ion-channel IPR006202 Neurotransmitter-gated ion-channel ligand-binding IPR008127 Glycine receptor alpha |
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PFAM |
PF02932
PF02931 |
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PRINTS |
PR00253
PR00252 PR01673 |
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PIRSF | |||||||||||||
SMART | |||||||||||||
TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q61603 | ||||||||||||
PhosphoSite | PhosphoSite- | ||||||||||||
TrEMBL | Q2TB05 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 14657 | ||||||||||||
UniGene | Mm.215168 | ||||||||||||
RefSeq | NP_034427 | ||||||||||||
MGI ID | |||||||||||||
MGI Symbol | Glra4 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS53195 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | AF462147 AL671887 BC110630 CH466616 DQ109809 X75850 X75851 X75852 X75853 | ||||||||||||
GenPept | AAI10631 AAL69899 AAZ17380 CAA53468 CAM17223 EDL23874 | ||||||||||||