InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sfxn2

Summary

InnateDB Protein

IDBP-173338.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sfxn2

Protein Name

sideroflexin 2

Synonyms

C79732; F630107H02Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000026011

InnateDB Gene

IDBG-173334 (Sfxn2)

Protein Structure

UniProt Annotation

Function

Potential iron transporter.

Subcellular Localization

Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in brain, heart, kidney, spleen, thymus, liver, stomach and skin. {ECO:0000269PubMed:11274051}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0008324	cation transmembrane transporter activity

Biological Process

GO:0006812	cation transport
GO:0008150	biological_process
GO:0055072	iron ion homeostasis
GO:0055085	transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2137678

InterPro

IPR004686 Tricarboxylate/iron carrier

PFAM

PF03820

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q925N2

PhosphoSite

PhosphoSite-Q925N2

TrEMBL

Q3UC14

UniProt Splice Variant

Entrez Gene

94279

UniGene

Mm.474521

RefSeq

NP_444426

MGI ID

MGI Symbol

Sfxn2

OMIM

CCDS

CCDS29880

HPRD

IMGT

EMBL

AF325261 AK150722 BC019808 CH466534

GenPept

AAH19808 AAK39429 BAE29800 EDL42008 EDL42009 EDL42010