InnateDB Protein
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IDBP-173405.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gamt
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Protein Name
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guanidinoacetate methyltransferase
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Synonyms
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AA571402; Spintz1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000020359
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InnateDB Gene
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IDBG-173403 (Gamt)
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Protein Structure
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Function |
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Subcellular Localization |
Cell projection, microvillus {ECO:0000269PubMed:8312439}. Note=Detected in microvilli of the epithelial cells lining the caput epididymis.
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Disease Associations |
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Tissue Specificity |
Highly expressed in testis, caput epididymis, ovary, and liver. In the testis, localized primarily in Sertoli cells. Expressed in brain with high levels in oligodendrocytes and olfactory ensheathing glia. Moderate levels of expression in astrocytes. {ECO:0000269PubMed:15245487, ECO:0000269PubMed:8312439}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
7 [view]
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Molecular Function |
Accession |
GO Term |
GO:0030731
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guanidinoacetate N-methyltransferase activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1098221
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InterPro |
IPR029063
S-adenosyl-L-methionine-dependent methyltransferase-like
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O35969
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PhosphoSite |
PhosphoSite-O35969
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
14431
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UniGene |
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RefSeq |
XP_006513284
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MGI ID |
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MGI Symbol |
Gamt
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AF010498
AF010499
AF015887
AK140688
AK158087
BC049233
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GenPept |
AAB81495
AAB81498
AAH49233
BAE24443
BAE34352
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