InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fnip1

Summary

InnateDB Protein

IDBP-173478.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fnip1

Protein Name

folliculin interacting protein 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000049026

InnateDB Gene

IDBG-173476 (Fnip1)

Protein Structure

UniProt Annotation

Function

May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1 (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Note=Colocalizes with FLCN in the cytoplasm. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005515	protein binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001932	regulation of protein phosphorylation
GO:0001934	positive regulation of protein phosphorylation
GO:0002327	immature B cell differentiation
GO:0002904	positive regulation of B cell apoptotic process
GO:0009267	cellular response to starvation
GO:0031929	TOR signaling
GO:0032007	negative regulation of TOR signaling
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0043087	regulation of GTPase activity
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043547	positive regulation of GTPase activity
GO:2000973	regulation of pro-B cell differentiation