Version 5.4
Mus musculus Protein: Nyap2
Summary
InnateDB Protein IDBP-173499.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nyap2
Protein Name RIKEN cDNA 9430031J16 gene
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000065468
InnateDB Gene IDBG-173497 (Nyap2)
Protein Structure
UniProt Annotation
Function Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis. {ECO:0000269PubMed:21946561}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed predominantly in brain where it is present in the neurons, but not in astrocytes or oligodendrites. {ECO:0000269PubMed:21946561}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0048812 neuron projection morphogenesis
Cellular Component
Protein Structure and Domains
PDB ID MGI:2443135
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BM65
PhosphoSite PhosphoSite-Q8BM65
TrEMBL
UniProt Splice Variant
Entrez Gene 241134
UniGene Mm.487598
RefSeq NP_766437
MGI ID
MGI Symbol Nyap2
OMIM
CCDS CCDS15095
HPRD
IMGT
EMBL AB429290 AC116105 AC131336 AC163450 AK034747 AK049778 AK129372 AK137094 BC082310
GenPept AAH82310 BAC28819 BAC33918 BAC98182 BAE23236 BAJ19139

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca