Version 5.4
Mus musculus Protein: Miox
Summary
InnateDB Protein IDBP-173582.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Miox
Protein Name myo-inositol oxygenase
Synonyms 0610009I10Rik; AI314022; Aldrl6; C85427; RSOR;
Species Mus musculus
Ensembl Protein ENSMUSP00000023282
InnateDB Gene IDBG-173580 (Miox)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Kidney specific. Renal proximal tubules. {ECO:0000269PubMed:10944187}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004033 aldo-keto reductase (NADP) activity
GO:0005506 iron ion binding
GO:0008199 ferric iron binding
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:0050113 inositol oxygenase activity
GO:0050661 NADP binding
Biological Process
GO:0019310 inositol catabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0016234 inclusion body
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1891725
InterPro IPR007828 Inositol oxygenase
PFAM PF05153
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QXN5
PhosphoSite PhosphoSite-Q9QXN5
TrEMBL
UniProt Splice Variant
Entrez Gene 56727
UniGene Mm.406532
RefSeq NP_064361
MGI ID 3BXD
MGI Symbol Miox
OMIM
CCDS CCDS27745
HPRD
IMGT
EMBL AF197127 AY738257 BC013543
GenPept AAF25202 AAH13543 AAV65815

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca