Mus musculus Protein: Esx1
Summary
InnateDB Protein IDBP-173695.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Esx1
Protein Name extraembryonic, spermatogenesis, homeobox 1
Synonyms Spx1;
Species Mus musculus
Ensembl Protein ENSMUSP00000074262
InnateDB Gene IDBG-173693 (Esx1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001568 blood vessel development
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0045892 negative regulation of transcription, DNA-templated
GO:0051726 regulation of cell cycle
GO:0060713 labyrinthine layer morphogenesis
GO:0060716 labyrinthine layer blood vessel development
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1096388
InterPro IPR000047 Helix-turn-helix motif
IPR001356 Homeobox domain
IPR009057 Homeodomain-like
PFAM PF00046
PRINTS PR00031
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL O88933
UniProt Splice Variant
Entrez Gene 13984
UniGene Mm.8017
RefSeq NP_031983
MGI ID
MGI Symbol Esx1
OMIM
CCDS CCDS53199
HPRD
IMGT
EMBL AF017735 AF085715 AL672275
GenPept AAC35366 AAD01622