Version 5.4
Mus musculus Protein: Cebpg
Summary
InnateDB Protein IDBP-173698.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cebpg
Protein Name CCAAT/enhancer binding protein (C/EBP), gamma
Synonyms C/EBP[g]; C/EBPgamma; GPE1-BP; Gpe1bp; Ig/EBP;
Species Mus musculus
Ensembl Protein ENSMUSP00000064963
InnateDB Gene IDBG-173696 (Cebpg)
Protein Structure
UniProt Annotation
Function Transcription factor that binds to the promoter and the enhancer of the immunoglobulin heavy chain. Binds to GPE1, a cis- acting element in the G-CSF gene promoter.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 3 [view]
Protein-DNA 9 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0001889 liver development
GO:0006337 nucleosome disassembly
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006955 immune response
GO:0016071 mRNA metabolic process
GO:0030183 B cell differentiation
GO:0042267 natural killer cell mediated cytotoxicity
GO:0043353 enucleate erythrocyte differentiation
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045078 positive regulation of interferon-gamma biosynthetic process
GO:0045739 positive regulation of DNA repair
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:104982
InterPro IPR004827 Basic-leucine zipper domain
PFAM PF00170
PF07716
PRINTS
PIRSF
SMART SM00338
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P53568
PhosphoSite PhosphoSite-P53568
TrEMBL Q54AJ1
UniProt Splice Variant
Entrez Gene 12611
UniGene Mm.465033
RefSeq
MGI ID
MGI Symbol Cebpg
OMIM
CCDS CCDS21144
HPRD
IMGT
EMBL AB012273 AB012275 AK050634 AK157391 AK159544 AK169583 AK171859 BC011319 CH466618 X55499
GenPept AAH11319 BAA25311 BAA25312 BAC34355 BAE34076 BAE35170 BAE41241 BAE42702 CAA39116 EDL03028

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca