InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc7a10

Summary

InnateDB Protein

IDBP-173735.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc7a10

Protein Name

solute carrier family 7 (cationic amino acid transporter, y+ system), member 10

Synonyms

AL024237; Asc-1; D7Bwg0847e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000001854

InnateDB Gene

IDBG-173733 (Slc7a10)

Protein Structure

UniProt Annotation

Function

Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse. {ECO:0000269PubMed:10734121}.

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Highly expressed in brain and lung, and to a lesser extent in placenta and small intestine. {ECO:0000269PubMed:10734121}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015171	amino acid transmembrane transporter activity
GO:0015175	neutral amino acid transmembrane transporter activity

Biological Process

GO:0003333	amino acid transmembrane transport
GO:0006810	transport
GO:0015804	neutral amino acid transport
GO:0042941	D-alanine transport
GO:0042942	D-serine transport
GO:0055085	transmembrane transport