Mus musculus Protein: Ints9
Summary
InnateDB Protein IDBP-173876.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ints9
Protein Name integrator complex subunit 9
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000045552
InnateDB Gene IDBG-173874 (Ints9)
Protein Structure
UniProt Annotation
Function Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0016787 hydrolase activity
Biological Process
GO:0016180 snRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0032039 integrator complex
Protein Structure and Domains
PDB ID MGI:1098533
InterPro IPR001279 Beta-lactamase-like
IPR022712 Beta-Casp domain
PFAM PF00753
PF10996
PRINTS
PIRSF
SMART SM00849
SM01027
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K114
PhosphoSite PhosphoSite-Q8K114
TrEMBL
UniProt Splice Variant
Entrez Gene 210925
UniGene
RefSeq NP_700463
MGI ID
MGI Symbol Ints9
OMIM
CCDS CCDS27210
HPRD
IMGT
EMBL AK038979 AK077634 AK136992 AK150195 BC028953 BC055700
GenPept AAH28953 AAH55700 BAC30191 BAC36917 BAE23199 BAE29371