InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Taf5

Summary

InnateDB Protein

IDBP-173928.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Taf5

Protein Name

TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000026027

InnateDB Gene

IDBG-173926 (Taf5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0004402	histone acetyltransferase activity
GO:0005515	protein binding
GO:0044212	transcription regulatory region DNA binding
GO:0046983	protein dimerization activity

Biological Process

GO:0006352	DNA-templated transcription, initiation
GO:0006355	regulation of transcription, DNA-templated
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0016573	histone acetylation

Cellular Component

GO:0005634	nucleus
GO:0005669	transcription factor TFIID complex
GO:0015629	actin cytoskeleton
GO:0033276	transcription factor TFTC complex
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

MGI:2442144

InterPro

IPR001680 WD40 repeat
IPR006594 LisH dimerisation motif
IPR007582 TFIID subunit, WD40-associated region
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat

PFAM

PF00400
PF04494

PRINTS

PR00320

PIRSF

SMART

SM00320
SM00667

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt