InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sumf1

Summary

InnateDB Protein

IDBP-174252.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sumf1

Protein Name

sulfatase modifying factor 1

Synonyms

AA543204; AI463102; AI851573; FGE;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032191

InnateDB Gene

IDBG-174250 (Sumf1)

Protein Structure

UniProt Annotation

Function

Using molecular oxygen and an unidentified reducing agent, oxidizes a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also called C(alpha)-formylglycine. Known substrates include GALNS, ARSA, STS and ARSE (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum lumen {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016491	oxidoreductase activity
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding