Mus musculus Protein: Slc19a3 | |||||||||
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Summary | |||||||||
InnateDB Protein | IDBP-174272.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Slc19a3 | ||||||||
Protein Name | solute carrier family 19 (sodium/hydrogen exchanger), member 3 | ||||||||
Synonyms | A230084E24Rik; AI788884; ThTr2; | ||||||||
Species | Mus musculus | ||||||||
Ensembl Protein | ENSMUSP00000041683 | ||||||||
InnateDB Gene | IDBG-174270 (Slc19a3) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | Mediates high affinity thiamine uptake, propably via a proton anti-port mechanism. Has no folate transport activity (By similarity). {ECO:0000250}. | ||||||||
Subcellular Localization | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | High expression in kidney, brain, lung and small intestine. | ||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||
PDB ID | MGI:1931307 | ||||||||
InterPro |
IPR002666
Reduced folate carrier IPR011701 Major facilitator superfamily IPR016196 Major facilitator superfamily domain, general substrate transporter |
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PFAM |
PF01770
PF07690 |
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PRINTS | |||||||||
PIRSF |
PIRSF028739
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SMART | |||||||||
TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | Q99PL8 | ||||||||
PhosphoSite | PhosphoSite-Q99PL8 | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 80721 | ||||||||
UniGene | Mm.261542 | ||||||||
RefSeq | NP_085033 | ||||||||
MGI ID | |||||||||
MGI Symbol | Slc19a3 | ||||||||
OMIM | |||||||||
CCDS | CCDS15101 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | AF271634 BC109154 BC109155 | ||||||||
GenPept | AAG53880 AAI09155 AAI09156 | ||||||||