Version 5.4
Mus musculus Protein: Vps45
Summary
InnateDB Protein IDBP-174330.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vps45
Protein Name vacuolar protein sorting 45 (yeast)
Synonyms AI462172; AW554165; mVps45;
Species Mus musculus
Ensembl Protein ENSMUSP00000015891
InnateDB Gene IDBG-174328 (Vps45)
Protein Structure
UniProt Annotation
Function May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network.
Subcellular Localization Golgi apparatus membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Associated with Golgi/endosomal vesicles and the trans-Golgi network.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006904 vesicle docking involved in exocytosis
GO:0008150 biological_process
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:891965
InterPro IPR001619 Sec1-like protein
PFAM PF00995
PRINTS
PIRSF PIRSF005715
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P97390
PhosphoSite PhosphoSite-P97390
TrEMBL
UniProt Splice Variant
Entrez Gene 22365
UniGene Mm.263185
RefSeq NP_038869
MGI ID
MGI Symbol Vps45
OMIM
CCDS CCDS17628
HPRD
IMGT
EMBL BC012691 BC058528 U66865
GenPept AAB37577 AAH12691 AAH58528

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca