InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Krtap7-1

Summary

InnateDB Protein

IDBP-174444.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Krtap7-1

Protein Name

keratin associated protein 7-1

Synonyms

5430433J05Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000054720

InnateDB Gene

IDBG-174442 (Krtap7-1)

Protein Structure

UniProt Annotation

Function

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005882	intermediate filament

Protein Structure and Domains

PDB ID

MGI:1918613

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D3I6

PhosphoSite

PhosphoSite-Q9D3I6

TrEMBL

UniProt Splice Variant

Entrez Gene

71363

UniGene

Mm.158680

RefSeq

NP_082047

MGI ID

MGI Symbol

Krtap7-1

OMIM

CCDS

CCDS49902

HPRD

IMGT

EMBL

AK017387

GenPept

BAB30724