Mus musculus Protein: Cfb
Summary
InnateDB Protein IDBP-174549.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cfb
Protein Name complement factor B
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000025229
InnateDB Gene IDBG-488478 (Cfb)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006956 complement activation
GO:0006957 complement activation, alternative pathway
GO:0008283 cell proliferation
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:105975
InterPro IPR000436 Sushi/SCR/CCP
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR002035 von Willebrand factor, type A
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR011360 Complement B/C2
PFAM PF00084
PF00089
PF00092
PRINTS PR00722
PIRSF PIRSF001154
SMART SM00032
SM00020
SM00327
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3UEG8
UniProt Splice Variant
Entrez Gene 14962
UniGene Mm.653
RefSeq NP_032224
MGI ID
MGI Symbol Cfb
OMIM
CCDS CCDS28663
HPRD
IMGT
EMBL AF049850 AF109906 AK149531 BC005451 CH466666 CT025759 K01496 K01497 K01498 M57890 M60629 M60630 M60631 M60632 M60633 M60634 M60635 M60636 M60637 M60638 M60639 M60640 M60641 M60642 M60643 M60644 M60645 M60646
GenPept AAA37379 AAA39549 AAA39550 AAA39551 AAA63293 AAC05283 AAC84160 AAH05451 BAE28943 EDL26738